Erythroplasia of queyrat is an early form of skin cancer found on the penis. Erythroplasia of queyrat treated with topical 5 fluorouracil. Nov 07, 2019 erythroplasia of queyrat eq is an in situ squamous cell carcinoma of the penis. Il principale fattore eziologico e rappresentato dallinfezione da alcuni tipi di papillomavirus oncogeni hpv. Eritroplasia di queyrat malattia di bowen del glande nasce dalla epitelio mucocutanea del pene. Happle r 1977 surgical treatment of erythroplasia of queyrat. Erythroplakia is a clinical term to describe any erythematous red area on a mucous membrane, that cannot be attributed to any other pathology 805 the term erythroplasia was coined by louis queyrat to describe a precancerous red lesion of the penis. The cause may be longstanding irritation of the penis under the foreskin. Removal of a tissue sample for examination under a microscope biopsy confirms the diagnosis. While not cancer itself, erythroplasia of queyrat can become cancerous if left untreated. The cancer is called squamous cell carcinoma in situ. Erythroplasia of queyrat is a rare in situ carcinoma of the uncircumcised man and its treatment depends on the extent and location of the lesion.
Also, mohs micrographic surgery has been used in the treatment of erythroplasia of queyrat. David weedon ao md frcpa fcaphon, in weedons skin pathology third edition, 2010. We describe the case of a 68 years old patient, with clinical and histological diagnosis of erythroplasia of queyrat. Sunlight exposure and immunosuppression are risk factors for scc of the skin, with chronic sun exposure being the strongest environmental risk factor. I pazienti non circoncisi sono i soggetti a maggior rischio. Treatment of erythroplasia of queyrat often involves removal or destruction of the lesion. It mainly occurs in uncircumcised males, over the age of 40. Erythroplasia of queyrat is a clinical expression of carcinoma in situ of the penis. Conejomir js, munoz ma, linares m, rodriguez l, serrano a. Poor hygiene and local irritation, as well as coinfection with hpv8. Erythroplasia of queyrat eq is an in situ squamous cell carcinoma of the penis.
Given the size and location of the lesion, preventing the surgical option, we performed the treatment with co2 laser. Depending upon the context, this term may refer specifically to carcinoma in situ of. Bowens disease of the penis bdp red or occasionally hyperpigmented scaly patches and plaques of the keratinised penis. Poor hygiene and local irritation, as well as coinfection with hpv8 and hpv16, are potential risk factors. Pdf we report a 33yearold male patient diagnosed with erythroplasia of queyrat. I sintomi principali sono una eruzione cutanea rossa e irritazione sulla punta del pene. A biopsy with subsequent histopathological examination is. Erythroplasia of queyrat is a particular type of bowens disease that can arise on the glans or prepuce in males. Erythroplasia of queyrat treated with topical 5fluorouracil ncbi. Carbon dioxide laser treatment of erythroplasia of queyrat. Erythroplasia of queyrat eq is a rare in situ squamous cell carcinoma.
Squamous cell cancer in situ can occur on any part of the body. Basal cell carcinoma of the penis is usually located along the penile shaft. The use of fractional co2 laser therapy for the treatment of an in situ. Placa eritematosa, sobreelevada rojiza en glande y prepucio. Erythroplasia of queyrat bowen disease of the glans penis. Erythroplasia of queyrat an overview sciencedirect topics.
Methods employed include cryotherapy, laser ablation, and surgical excision. Il glande e prepuzio sono piu comunemente coinvolti. Zoons balanitis, penile intraepithelial neoplasiacarcinoma in situerythroplasia of queyrat eq, squamous cell cancer of the penis, malignant melanoma of the penis and rarely basal cell cancer of the penis. Erythroplasia of queyrat and bowenoid papulosis primary. Erythroplasia of queyrat treated with imiquimod 5% cream. Progression to invasive carcinoma may occur, and spontaneous regression is unlikely. Squamous cell carcinoma is the secondmost common cancer of the skin after basalcell carcinoma but more common than melanoma. This term is used only when the cancer occurs on the penis. Erythroplasia of queyrat eq is a rare in situ squamous cell carcinoma scc of the glans penis, which typically appears. The glans is the predominant location of this lesion, and its nonspecific presentation a sharply defined red patch or plaque, may often lead to a misdiagnosis as one of many mucosal dermatoses.
Erythroplasia of queyrat usually occurs in uncircumcised men. May 29, 2012 differential diagnosis included balanitis example. Erythroplasia of queyrat treated with topical 5fluorouracil scielo. Selected cases of eq have been treated successfully using 5fluorouracil. Erythroplasia of queyrat eq is a carcinoma in situ of the mucosal surface of the penis. Lesions can occasionally have a warty or crusty appearance. Pdf erythroplasia of queyrat treated with topical 5. Single or multiple, nontender, red, shiny patches or plaques of the mucosal penis ie the glans and prepuce of the uncircumcised. Erythroplasia of queyrat is an in situ squamous cell carcinoma of the glans penis. Oltre alla classica forma di eritroplasia, con margini indefiniti, situata sovente sul pavimento della bocca negli uomini e sulla lingue nelle donne, esiste unaltra forma, denominata eritroplasia di queyrat, che colpisce i genitali maschili, in. This gave rise to the term erythoplasia of queyrat. Pdf erythroplasia of queyrat treated with topical 5fluorouracil. Carcinoma squamocellulare insitu eritroplasia di queyrat.